Ayman El-Guindy

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Company: Viracta Therapeutics

Job title: Chief Scientific Officer


Activation of Latent Oncogenic Viruses as a Form of Targeted Cancer Therapy 12:00 pm

Outlining the Epstein-Barr virus (EBV), a ubiquitous lymphotropic herpesvirus, associated with a heterogenous group of malignancies. Demonstrating how Nanatinostat induces expression of the EBV protein kinase, BGLF4, which activates the antiviral ganciclovir via phosphorylation to block DNA synthesis and trigger apoptosis. Discussing our phase 1b/2 clinical data which demonstrated promising efficacy and safety in patients…Read more

day: Day Two

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