Neil Michaud

Neil Michaud

Company: Epizyme

Job title: Senior Director, Translational Medicine


Innovative leader with extensive knowledge of oncology small molecule and biologics drug discovery and development, spanning idea to early stage clinical trials. 
Biologist by training with in depth experience with target identification and validation, biochemical and cell assay development supporting LI/LO/CS, in vivo PK/PD/efficacy modeling, and translational medicine, including patient selection and response biomarker development. 
Successful Project Team Leader and Lead Biologist advancing numerous small molecule and antibody programs, including delivery of multiple antibody projects into clinical development. 
Translational medicine expertise, including formulation of plans to deliver clinical POC in solid and hematological tumor indications, development of patient selection and response biomarkers, analysis of clinical trial data, and contribution to clinical protocols, IB, and regulatory documents. 


Case Study: The Tazemetostat Story 2:45 pm

Designing a successful clinical trial – balancing efficacy and safety Patient cohorts based on a diagnostic tool that identifies patients with specific EZH2 mutations Future implications, plans and the move towards precision medicine in oncologyRead more

day: Virtual Conference Day

Panel: Toxicity and Off-Target Effects 2:15 pm

Overcoming the obstacles of toxicity regardless of target  Techniques for monitoring toxicity and balancing this with efficacy  Debating the dangers of off-target effects versus on-target effects Read more

day: Virtual Conference Day

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