Laura Banaszynski

Laura Banaszynski

Company: University of Texas Southwestern Medical Center

Job title: Principal Investigator

Seminars:

Phosphorylation of Histone H3.3 at Serine 31 Promotes p300 Activity 1:30 pm

H3.3-specific S31 phosphorylation stimulates activity of the acetyltransferase p300 in trans, suggesting that H3.3 acts as a nucleosomal cofactor for p300 at enhancers Depletion of H3.3 from mESCs results in a substantial reduction of acetylation on histone H3 at lysine 27 (H3K27ac) at enhancers Cells lacking H3.3 demonstrate reduced capacity to acetylate enhancers that are…Read more

day: Day Two

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